HISTORY OF ATOPIC DERMATITIS AND ITS RELATIONSHIP WITH FOOD ALLERGY
Keywords:
atopic dermatitis, food allergy, immunoglobulin E, skin barrier, diet therapy.Abstract
This article reviews the history, pathogenesis, and association of atopic dermatitis (AD) with food allergies. Although AD has been observed since ancient times, the scientific term was established in the 20th century. The disease is a chronic and relapsing inflammatory process that often begins in childhood. Its development is influenced by a complex interaction of genetic predisposition, impaired skin barrier function, immune system imbalance, and environmental factors. Studies show that AD occurs in 15–20% of children and 2–10% of adults. Food allergy may be a factor in atopic dermatitis, but it is not observed in all patients. Therefore, diet therapy in the treatment of AD is effective only in cases where clinical signs of allergy are present. The article reviews the relationship between AD and food allergy, diagnostic approaches, and treatment tactics on a scientific basis based on an analysis of modern literature.
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